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Impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis

OBJECTIVES: This study is aimed to determine the impact of liver disease severity on the outcome of patients undergoing endourological procedures for urolithiasis, and to understand the factors that are helpful in improving the outcome. MATERIALS AND METHODS: We retrospectively analyzed the records...

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Autores principales: Sharma, Anil, Sindwani, Gaurav, Arora, Vinod, Bhardwaj, Ankit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132189/
https://www.ncbi.nlm.nih.gov/pubmed/35633855
http://dx.doi.org/10.1097/CU9.0000000000000088
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author Sharma, Anil
Sindwani, Gaurav
Arora, Vinod
Bhardwaj, Ankit
author_facet Sharma, Anil
Sindwani, Gaurav
Arora, Vinod
Bhardwaj, Ankit
author_sort Sharma, Anil
collection PubMed
description OBJECTIVES: This study is aimed to determine the impact of liver disease severity on the outcome of patients undergoing endourological procedures for urolithiasis, and to understand the factors that are helpful in improving the outcome. MATERIALS AND METHODS: We retrospectively analyzed the records of patients with chronic liver disease who underwent endourological procedures between January 2014 and February 2020. Inpatient records and charts were assessed for age, sex, height, weight, body mass index, model for end-stage liver disease (MELD) score, Child-Turcotte-Pugh score, type of procedure and anesthesia, intensive care unit (ICU) stay, duration of hospitalization, number, size, and position of stones, and postoperative complications such as hematuria, sepsis, and secondary procedures. Data are presented as mean ± standard deviation or frequency. The chi-square test was applied to determine the exact association between categorical data and Student t-test or Mann-Whitney U test as appropriate for continuous data. Statistical significance was set at p < 0.05. RESULTS: Hospital and ICU stay as well as administration of different blood products were significantly longer in the Child C than in the Child A and B categories (p < 0.001). Two patients in the Child C category died, while 3 left the hospital against medical advice. The duration of ICU stay and blood products administered increased with augmenting MELD scores. The durations of hospitalization and blood product administration were significantly higher in patients with an MELD score ≥20 than in the group with MELD score <20. CONCLUSIONS: Hospital and ICU stay and blood product administration were significantly higher in Child C than in Child A and B class patients. Hospitalization duration and blood product administration were significantly higher in patients with an MELD score ≥20.
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spelling pubmed-91321892022-05-27 Impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis Sharma, Anil Sindwani, Gaurav Arora, Vinod Bhardwaj, Ankit Curr Urol Advances in Urinary Calculi Management: Original Articles OBJECTIVES: This study is aimed to determine the impact of liver disease severity on the outcome of patients undergoing endourological procedures for urolithiasis, and to understand the factors that are helpful in improving the outcome. MATERIALS AND METHODS: We retrospectively analyzed the records of patients with chronic liver disease who underwent endourological procedures between January 2014 and February 2020. Inpatient records and charts were assessed for age, sex, height, weight, body mass index, model for end-stage liver disease (MELD) score, Child-Turcotte-Pugh score, type of procedure and anesthesia, intensive care unit (ICU) stay, duration of hospitalization, number, size, and position of stones, and postoperative complications such as hematuria, sepsis, and secondary procedures. Data are presented as mean ± standard deviation or frequency. The chi-square test was applied to determine the exact association between categorical data and Student t-test or Mann-Whitney U test as appropriate for continuous data. Statistical significance was set at p < 0.05. RESULTS: Hospital and ICU stay as well as administration of different blood products were significantly longer in the Child C than in the Child A and B categories (p < 0.001). Two patients in the Child C category died, while 3 left the hospital against medical advice. The duration of ICU stay and blood products administered increased with augmenting MELD scores. The durations of hospitalization and blood product administration were significantly higher in patients with an MELD score ≥20 than in the group with MELD score <20. CONCLUSIONS: Hospital and ICU stay and blood product administration were significantly higher in Child C than in Child A and B class patients. Hospitalization duration and blood product administration were significantly higher in patients with an MELD score ≥20. Lippincott Williams & Wilkins 2022-03 2022-02-08 /pmc/articles/PMC9132189/ /pubmed/35633855 http://dx.doi.org/10.1097/CU9.0000000000000088 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Advances in Urinary Calculi Management: Original Articles
Sharma, Anil
Sindwani, Gaurav
Arora, Vinod
Bhardwaj, Ankit
Impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis
title Impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis
title_full Impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis
title_fullStr Impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis
title_full_unstemmed Impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis
title_short Impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis
title_sort impact of liver disease severity on outcomes of patients undergoing endourological procedures for urolithiasis
topic Advances in Urinary Calculi Management: Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132189/
https://www.ncbi.nlm.nih.gov/pubmed/35633855
http://dx.doi.org/10.1097/CU9.0000000000000088
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