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PEGDA microencapsulated allogeneic islets reverse canine diabetes without immunosuppression

BACKGROUND: Protection of islets without systemic immunosuppression has been a long-sought goal in the islet transplant field. We conducted a pilot biocompatibility/safety study in healthy dogs followed by a dose-finding efficacy study in diabetic dogs using polyethylene glycol diacrylate (PEGDA) mi...

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Detalles Bibliográficos
Autores principales: Harrington, Stephen, Karanu, Francis, Ramachandran, Karthik, Williams, S. Janette, Stehno-Bittel, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132281/
https://www.ncbi.nlm.nih.gov/pubmed/35613086
http://dx.doi.org/10.1371/journal.pone.0267814

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