Cargando…
PEGDA microencapsulated allogeneic islets reverse canine diabetes without immunosuppression
BACKGROUND: Protection of islets without systemic immunosuppression has been a long-sought goal in the islet transplant field. We conducted a pilot biocompatibility/safety study in healthy dogs followed by a dose-finding efficacy study in diabetic dogs using polyethylene glycol diacrylate (PEGDA) mi...
Autores principales: | Harrington, Stephen, Karanu, Francis, Ramachandran, Karthik, Williams, S. Janette, Stehno-Bittel, Lisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132281/ https://www.ncbi.nlm.nih.gov/pubmed/35613086 http://dx.doi.org/10.1371/journal.pone.0267814 |
Ejemplares similares
-
A Versatile Microencapsulation Platform for Hyaluronic Acid and Polyethylene Glycol
por: Harrington, Stephen, et al.
Publicado: (2021) -
Improved yield of canine islet isolation from deceased donors
por: Harrington, Stephen, et al.
Publicado: (2017) -
Small human islets comprised of more β-cells with higher insulin content than large islets
por: Farhat, Bilal, et al.
Publicado: (2013) -
A replacement for islet equivalents with improved reliability and validity
por: Huang, Han-Hung, et al.
Publicado: (2012) -
KU-32, a Novel Drug for Diabetic Neuropathy, Is Safe for Human Islets and Improves In Vitro Insulin Secretion and Viability
por: Farmer, Kevin, et al.
Publicado: (2012)