A multicentre study on spontaneous in-cage activity and micro-environmental conditions of IVC housed C57BL/6J mice during consecutive cycles of bi-weekly cage-change

Mice respond to a cage change (CC) with altered activity, disrupted sleep and increased anxiety. A bi-weekly cage change is, therefore, preferred over a shorter CC interval and is currently the prevailing routine for Individually ventilated cages (IVCs). However, the build-up of ammonia (NH(3)) duri...

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Detalles Bibliográficos
Autores principales: Ulfhake, B., Lerat, H., Honetschlager, J., Pernold, K., Rynekrová, M., Escot, K., Recordati, C., Kuiper, R. V., Rosati, G., Rigamonti, M., Zordan, S., Prins, J.-B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132304/
https://www.ncbi.nlm.nih.gov/pubmed/35613182
http://dx.doi.org/10.1371/journal.pone.0267281

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