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Structural basis of autoinhibition of the human NHE3-CHP1 complex

Sodium-proton exchanger 3 (NHE3/SLC9A3) located in the apical membrane of renal and gastrointestinal epithelia mediates salt and fluid absorption and regulates pH homeostasis. As an auxiliary regulatory factor of NHE proteins, calcineurin B homologous protein 1 (CHP1) facilitates NHE3 maturation, pl...

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Detalles Bibliográficos
Autores principales:	Dong, Yanli, Li, Hang, Ilie, Alina, Gao, Yiwei, Boucher, Annie, Zhang, Xuejun Cai, Orlowski, John, Zhao, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132474/ https://www.ncbi.nlm.nih.gov/pubmed/35613257 http://dx.doi.org/10.1126/sciadv.abn3925

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