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The Potential Role for Impaired Mucosal Integrity in the Generation of Esophageal Pain Using Capsaicin in Humans: An Explorative Study

INTRODUCTION: Esophageal pain is mediated by sensory nerves, most importantly by the activation of the transient receptor potential vanilloid 1 (TRPV1) capsaicin receptor. TRPV1 is activated and sensitized by a broad range of pungent compounds, as well as inflammatory mediators and tissue irritants....

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Detalles Bibliográficos
Autores principales: Alleleyn, Annick M.E., Keszthelyi, Daniel, Rinsma, Nicolaas F., Csekő, Kata, Kajtár, Béla, Helyes, Zsuzsanna, Winkens, Bjorn, Masclee, Adrian A.M., Conchillo, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132534/
https://www.ncbi.nlm.nih.gov/pubmed/35351835
http://dx.doi.org/10.14309/ctg.0000000000000488

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