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Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations

Antibodies that target immune checkpoints such as cytotoxic T lymphocyte antigen 4 (CTLA‐4) and the programmed cell death protein 1/ligand 1 (PD-1/PD-L1) are now a treatment option for multiple cancer types. However, as a monotherapy, objective responses only occur in a minority of patients. Chemoth...

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Detalles Bibliográficos
Autores principales:	Principe, Nicola, Aston, Wayne J., Hope, Danika E., Tilsed, Caitlin M., Fisher, Scott A., Boon, Louis, Dick, Ian M., Chin, Wee Loong, McDonnell, Alison M., Nowak, Anna K., Lake, Richard A., Chee, Jonathan, Lesterhuis, Willem Joost
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132586/ https://www.ncbi.nlm.nih.gov/pubmed/35634282 http://dx.doi.org/10.3389/fimmu.2022.872295

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