Macrophage Differentiation and Polarization Regulate the Release of the Immune Checkpoint Protein V-Domain Ig Suppressor of T Cell Activation

Recently, the V-domain immunoglobulin suppressor of T-cell activation (VISTA) was identified as a negative immune checkpoint regulator (NCR) that is mainly expressed in hematopoietic cells. Preclinical studies have shown that VISTA blockade results in impeded tumor growth and improved survival. Neve...

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Detalles Bibliográficos
Autores principales: Noubissi Nzeteu, Gaetan Aime, Schlichtner, Stephanie, David, Sulamith, Ruppenstein, Aylin, Fasler-Kan, Elizaveta, Raap, Ulrike, Sumbayev, Vadim V., Gibbs, Bernhard F., Meyer, N. Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132587/
https://www.ncbi.nlm.nih.gov/pubmed/35634346
http://dx.doi.org/10.3389/fimmu.2022.837097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132587/
https://www.ncbi.nlm.nih.gov/pubmed/35634346
http://dx.doi.org/10.3389/fimmu.2022.837097

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