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Antiviral activity of chitosan nanoparticles encapsulating silymarin (Sil–CNPs) against SARS-CoV-2 (in silico and in vitro study)

To develop a specific treatment against COVID-19, we investigated silymarin–chitosan nanoparticles (Sil–CNPs) as an antiviral agent against SARS-CoV-2 using in silico and in vitro approaches. Docking of Sil and CNPs was carried out against SARS-CoV-2 spike protein using AutoDock Vina. CNPs and Sil–C...

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Detalles Bibliográficos
Autores principales:	Loutfy, Samah A., Abdel-Salam, Ahmed I., Moatasim, Yassmin, Gomaa, Mokhtar R., Abdel Fattah, Nasra F., Emam, Merna H., Ali, Fedaa, ElShehaby, Hasnaa A., Ragab, Eman A., Alam El-Din, Hanaa M., Mostafa, Ahmed, Ali, Mohamed A., Kasry, Amal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132606/ https://www.ncbi.nlm.nih.gov/pubmed/35685696 http://dx.doi.org/10.1039/d2ra00905f

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