Poor T-cell receptor β repertoire diversity early posttransplant for severe combined immunodeficiency predicts failure of immune reconstitution

BACKGROUND: Development of a diverse T-cell receptor β (TRB) repertoire is associated with immune recovery following hematopoietic cell transplantation (HCT) for severe combined immunodeficiency (SCID). High-throughput sequencing of the TRB repertoire allows evaluation of clonotype dynamics during i...

Descripción completa

Detalles Bibliográficos
Autores principales: Delmonte, Ottavia M., Castagnoli, Riccardo, Yu, Jason, Dvorak, Christopher C., Cowan, Morton J., Dávila Saldaña, Blachy J., De Ravin, Suk See, Mamcarz, Ewelina, Chang, Catherine K., Daley, Stephen R., Griffith, Linda M., Notarangelo, Luigi D., Puck, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132846/
https://www.ncbi.nlm.nih.gov/pubmed/34384841
http://dx.doi.org/10.1016/j.jaci.2021.07.029

Ejemplares similares

Ejemplares similares