Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes

Human coronavirus OC43 is a globally circulating common cold virus sustained by recurrent reinfections. How it persists in the population and defies existing herd immunity is unknown. Here we focus on viral glycoprotein S, the target for neutralizing antibodies, and provide an in-depth analysis of i...

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Detalles Bibliográficos
Autores principales: Wang, Chunyan, Hesketh, Emma L., Shamorkina, Tatiana M., Li, Wentao, Franken, Peter J., Drabek, Dubravka, van Haperen, Rien, Townend, Sarah, van Kuppeveld, Frank J. M., Grosveld, Frank, Ranson, Neil A., Snijder, Joost, de Groot, Raoul J., Hurdiss, Daniel L., Bosch, Berend-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132891/
https://www.ncbi.nlm.nih.gov/pubmed/35614127
http://dx.doi.org/10.1038/s41467-022-30658-0

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