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Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism
‘Affinity escape’: Novel SARS-CoV-2 variants may escape immunity by raising the RBD-ACE2 affinity high enough to outcompete the avidity of neutralizing antibodies.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132958/ https://www.ncbi.nlm.nih.gov/pubmed/35614112 http://dx.doi.org/10.1038/s41541-022-00479-9 |
| _version_ | 1784713492539899904 |
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| author | Bachmann, Martin F. Mohsen, Mona O. Speiser, Daniel E. |
| author_facet | Bachmann, Martin F. Mohsen, Mona O. Speiser, Daniel E. |
| author_sort | Bachmann, Martin F. |
| collection | PubMed |
| description | ‘Affinity escape’: Novel SARS-CoV-2 variants may escape immunity by raising the RBD-ACE2 affinity high enough to outcompete the avidity of neutralizing antibodies. |
| format | Online Article Text |
| id | pubmed-9132958 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-91329582022-05-27 Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism Bachmann, Martin F. Mohsen, Mona O. Speiser, Daniel E. NPJ Vaccines Comment ‘Affinity escape’: Novel SARS-CoV-2 variants may escape immunity by raising the RBD-ACE2 affinity high enough to outcompete the avidity of neutralizing antibodies. Nature Publishing Group UK 2022-05-25 /pmc/articles/PMC9132958/ /pubmed/35614112 http://dx.doi.org/10.1038/s41541-022-00479-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
| spellingShingle | Comment Bachmann, Martin F. Mohsen, Mona O. Speiser, Daniel E. Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism |
| title | Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism |
| title_full | Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism |
| title_fullStr | Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism |
| title_full_unstemmed | Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism |
| title_short | Increased receptor affinity of SARS-CoV-2: a new immune escape mechanism |
| title_sort | increased receptor affinity of sars-cov-2: a new immune escape mechanism |
| topic | Comment |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132958/ https://www.ncbi.nlm.nih.gov/pubmed/35614112 http://dx.doi.org/10.1038/s41541-022-00479-9 |
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