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Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy

A major reason for the high mortality of patients with bladder cancer (BC) is that chemotherapy and surgery are only effective for very limited patients. Thus, developing novel treatment options becomes an urgent need for improving clinical outcomes and the quality of life for BC patients. Here, we...

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Detalles Bibliográficos
Autores principales: Xiao, Di, Hu, Xin, Peng, Mei, Deng, Jun, Zhou, Sichun, Xu, Simeng, Wu, Jingtao, Yang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132982/
https://www.ncbi.nlm.nih.gov/pubmed/35614042
http://dx.doi.org/10.1038/s41419-022-04937-z