Cargando…
Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy
A major reason for the high mortality of patients with bladder cancer (BC) is that chemotherapy and surgery are only effective for very limited patients. Thus, developing novel treatment options becomes an urgent need for improving clinical outcomes and the quality of life for BC patients. Here, we...
Autores principales: | Xiao, Di, Hu, Xin, Peng, Mei, Deng, Jun, Zhou, Sichun, Xu, Simeng, Wu, Jingtao, Yang, Xiaoping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9132982/ https://www.ncbi.nlm.nih.gov/pubmed/35614042 http://dx.doi.org/10.1038/s41419-022-04937-z |
Ejemplares similares
-
Synergistic augmentation of osimertinib‐induced autophagic death by proguanil or rapamycin in bladder cancer
por: Xiao, Di, et al.
Publicado: (2023) -
Metformin targets Clusterin to control lipogenesis and inhibit the growth of bladder cancer cells through SREBP-1c/FASN axis
por: Deng, Jun, et al.
Publicado: (2021) -
Proguanil synergistically sensitizes ovarian cancer cells to olaparib by increasing DNA damage and inducing apoptosis
por: Wu, Yan, et al.
Publicado: (2022) -
Synthesis, Anti-Proliferative Evaluation and Mechanism of 4-Trifluoro Methoxy Proguanil Derivatives with Various Carbon Chain Length
por: Xu, Simeng, et al.
Publicado: (2021) -
Phenformin alone or combined with gefitinib inhibits bladder cancer via AMPK and EGFR pathways
por: Huang, Yanjun, et al.
Publicado: (2018)