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Association of B7‐H3 expression with racial ancestry, immune cell density, and androgen receptor activation in prostate cancer

BACKGROUND: B7 homolog 3 (B7‐H3) is an immunomodulatory molecule that is highly expressed in prostate cancer (PCa) and belongs to the B7 superfamily, which includes PD‐L1. Immunotherapies (antibodies, antibody‐drug conjugates, and chimeric antigen receptor T cells) targeting B7‐H3 are currently in c...

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Detalles Bibliográficos
Autores principales: Mendes, Adrianna A., Lu, Jiayun, Kaur, Harsimar B., Zheng, Siqun L., Xu, Jianfeng, Hicks, Jessica, Weiner, Adam B., Schaeffer, Edward M., Ross, Ashley E., Balk, Steven P., Taplin, Mary‐Ellen, Lack, Nathan A., Tekoglu, Emirhan, Maynard, Janielle P., De Marzo, Angelo M., Antonarakis, Emmanuel S., Sfanos, Karen S., Joshu, Corinne E., Shenderov, Eugene, Lotan, Tamara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133095/
https://www.ncbi.nlm.nih.gov/pubmed/35333400
http://dx.doi.org/10.1002/cncr.34190