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Parsing the role of NSP1 in SARS-CoV-2 infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to shutoff of protein synthesis, and nsp1, a central shutoff factor in coronaviruses, inhibits cellular mRNA translation. However, the diverse molecular mechanisms employed by nsp1 as well as its functional importance are unresolved....
Autores principales: | Fisher, Tal, Gluck, Avi, Narayanan, Krishna, Kuroda, Makoto, Nachshon, Aharon, Hsu, Jason C., Halfmann, Peter J., Yahalom-Ronen, Yfat, Tamir, Hadas, Finkel, Yaara, Schwartz, Michal, Weiss, Shay, Tseng, Chien-Te K., Israely, Tomer, Paran, Nir, Kawaoka, Yoshihiro, Makino, Shinji, Stern-Ginossar, Noam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133101/ https://www.ncbi.nlm.nih.gov/pubmed/35671758 http://dx.doi.org/10.1016/j.celrep.2022.110954 |
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