Cargando…
Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose
Opioid use disorder is a highly heterogeneous disease driven by a variety of genetic and environmental risk factors which have yet to be fully elucidated. Opioid overdose, the most severe outcome of opioid use disorder, remains the leading cause of accidental death in the United States. We interroga...
Autores principales: | Corradin, Olivia, Sallari, Richard, Hoang, An T., Kassim, Bibi S, Hutta, Gabriella Ben, Cuoto, Lizette, Quach, Bryan C., Lovrenert, Katreya, Hays, Cameron, Gryder, Berkley E., Iskhakova, Marina, Cates, Hannah, Song, Yanwei, Bartels, Cynthia F., Hancock, Dana B., Mash, Deborah C., Johnson, Eric O., Akbarian, Schahram, Scacheri, Peter C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133127/ https://www.ncbi.nlm.nih.gov/pubmed/35301427 http://dx.doi.org/10.1038/s41380-022-01477-y |
Ejemplares similares
-
Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis
por: Pontius, W. Dean, et al.
Publicado: (2023) -
Single Nucleus Transcriptomics Reveals Pervasive Glial Activation in Opioid Overdose Cases
por: Wei, Julong, et al.
Publicado: (2023) -
Epigenetic convergence in the rising tide of opioid overdose deaths
por: Hays, Cameron F., et al.
Publicado: (2022) -
Epigenetic effects of high-fat diet on intestinal tumorigenesis in C57BL/6J-Apc(Min/+) mice
por: Qu, Dan C., et al.
Publicado: (2023) -
Enhancer variants: evaluating functions in common disease
por: Corradin, Olivia, et al.
Publicado: (2014)