The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies

Non-polyadenylated mRNAs of replication-dependent histones (RDHs) are synthesized by RNA polymerase II (Pol II) at histone locus bodies (HLBs). HLBs frequently associate with Cajal bodies (CBs), in which 3′-end processing factors for RDH genes are enriched; however, this association’s role in transc...

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Detalles Bibliográficos
Autores principales: Suzuki, Hidefumi, Abe, Ryota, Shimada, Miho, Hirose, Tomonori, Hirose, Hiroko, Noguchi, Keisuke, Ike, Yoko, Yasui, Nanami, Furugori, Kazuki, Yamaguchi, Yuki, Toyoda, Atsushi, Suzuki, Yutaka, Yamamoto, Tatsuro, Saitoh, Noriko, Sato, Shigeo, Tomomori-Sato, Chieri, Conaway, Ronald C., Conaway, Joan W., Takahashi, Hidehisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133132/
https://www.ncbi.nlm.nih.gov/pubmed/35614107
http://dx.doi.org/10.1038/s41467-022-30632-w

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