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Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features()

Lichen planopilaris and frontal fibrosing alopecia are primary scarring alopecias where diagnosis can be suggested by clinical and trichoscopy features, especially in the early stages, but scalp biopsy is the standard exam for definitive diagnosis. Frontal fibrosing alopecia is considered a variant...

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Autores principales: Fechine, Carolina Oliveira Costa, Valente, Neusa Yuriko Sakai, Romiti, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133245/
https://www.ncbi.nlm.nih.gov/pubmed/35379508
http://dx.doi.org/10.1016/j.abd.2021.08.008
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author Fechine, Carolina Oliveira Costa
Valente, Neusa Yuriko Sakai
Romiti, Ricardo
author_facet Fechine, Carolina Oliveira Costa
Valente, Neusa Yuriko Sakai
Romiti, Ricardo
author_sort Fechine, Carolina Oliveira Costa
collection PubMed
description Lichen planopilaris and frontal fibrosing alopecia are primary scarring alopecias where diagnosis can be suggested by clinical and trichoscopy features, especially in the early stages, but scalp biopsy is the standard exam for definitive diagnosis. Frontal fibrosing alopecia is considered a variant of lichen planopilaris, as the histopathological findings are similar, with a perifollicular lymphohistiocytic infiltrate, sometimes with a lichenoid pattern. A thorough clinical examination, trichoscopy and photographic documentation are essential to assess the evolution and therapeutic response. To date, there are no validated treatments or guidelines for these diseases, but there are recommendations that vary with the individual characteristics of each patient. This article presents a comprehensive review of the literature, including an update on topics related to the diagnosis, follow-up, histopathological aspects and available treatments for lichen planopilaris and frontal fibrosing alopecia, highlighting their similarities, differences and peculiarities.
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spelling pubmed-91332452022-05-26 Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features() Fechine, Carolina Oliveira Costa Valente, Neusa Yuriko Sakai Romiti, Ricardo An Bras Dermatol Review Lichen planopilaris and frontal fibrosing alopecia are primary scarring alopecias where diagnosis can be suggested by clinical and trichoscopy features, especially in the early stages, but scalp biopsy is the standard exam for definitive diagnosis. Frontal fibrosing alopecia is considered a variant of lichen planopilaris, as the histopathological findings are similar, with a perifollicular lymphohistiocytic infiltrate, sometimes with a lichenoid pattern. A thorough clinical examination, trichoscopy and photographic documentation are essential to assess the evolution and therapeutic response. To date, there are no validated treatments or guidelines for these diseases, but there are recommendations that vary with the individual characteristics of each patient. This article presents a comprehensive review of the literature, including an update on topics related to the diagnosis, follow-up, histopathological aspects and available treatments for lichen planopilaris and frontal fibrosing alopecia, highlighting their similarities, differences and peculiarities. Sociedade Brasileira de Dermatologia 2022 2022-04-02 /pmc/articles/PMC9133245/ /pubmed/35379508 http://dx.doi.org/10.1016/j.abd.2021.08.008 Text en © 2022 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Fechine, Carolina Oliveira Costa
Valente, Neusa Yuriko Sakai
Romiti, Ricardo
Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features()
title Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features()
title_full Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features()
title_fullStr Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features()
title_full_unstemmed Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features()
title_short Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features()
title_sort lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features()
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133245/
https://www.ncbi.nlm.nih.gov/pubmed/35379508
http://dx.doi.org/10.1016/j.abd.2021.08.008
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