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A bipartite graph-based expected networks approach identifies DDR genes not associated with TMB yet predictive of immune checkpoint blockade response

Immune checkpoint blockade (ICB) has had remarkable success for treatment of solid tumors. However, as only a subset of patients exhibit responses, there is a continued need for biomarker development. Numerous reports have shown a link between tumor mutational burden (TMB) and ICB response, while ot...

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Detalles Bibliográficos
Autores principales: Weir, William H., Mucha, Peter J., Kim, William Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133403/
https://www.ncbi.nlm.nih.gov/pubmed/35584624
http://dx.doi.org/10.1016/j.xcrm.2022.100602

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