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Post-Translational Modification of GPX4 is a Promising Target for Treating Ferroptosis-Related Diseases

Glutathione peroxidase 4 (GPX4) is one of the most important antioxidant enzymes. As the key regulator of ferroptosis, GPX4 has attracted considerable attention in the fields of cancer, cardiovascular, and neuroscience research in the past 10 years. How to regulate GPX4 activity has become a hot top...

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Detalles Bibliográficos
Autores principales: Cui, Can, Yang, Fei, Li, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133406/
https://www.ncbi.nlm.nih.gov/pubmed/35647032
http://dx.doi.org/10.3389/fmolb.2022.901565