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Gene therapy for female infertility: A farfetched dream or reality?

A major cause of infertility in women is impaired ovulation or oogenesis. In this issue of Cell Reports Medicine, Kanatsu-Shinohara et al.(1) demonstrate the potential of gene delivery with adeno-associated virus that can cross the blood-follicle barrier and restore oogenesis in congenitally inferti...

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Detalles Bibliográficos
Autores principales: Pathak, Subhajit, Sarangi, Pratiksha, Jayandharan, Giridhara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133461/
https://www.ncbi.nlm.nih.gov/pubmed/35584635
http://dx.doi.org/10.1016/j.xcrm.2022.100641
Descripción
Sumario:A major cause of infertility in women is impaired ovulation or oogenesis. In this issue of Cell Reports Medicine, Kanatsu-Shinohara et al.(1) demonstrate the potential of gene delivery with adeno-associated virus that can cross the blood-follicle barrier and restore oogenesis in congenitally infertile mice.