The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses

Recent genome-wide association studies (GWASs) of COVID-19 patients of European ancestry have identified genetic loci significantly associated with disease severity. Here, we employed the detailed clinical, immunological and multi-omics dataset of the Human Functional Genomics Project (HFGP) to expl...

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Detalles Bibliográficos
Autores principales: Kuijpers, Yunus, Chu, Xiaojing, Jaeger, Martin, Moorlag, Simone J. C. F. M., Koeken, Valerie A. C. M., Zhang, Bowen, de Nooijer, Aline, Grondman, Inge, Gupta, Manoj Kumar, Janssen, Nico, Mourits, Vera P., de Bree, L. Charlotte J., de Mast, Quirijn, van de Veerdonk, Frank L., Joosten, Leo A. B., Li, Yang, Netea, Mihai G., Xu, Cheng-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133558/
https://www.ncbi.nlm.nih.gov/pubmed/35634344
http://dx.doi.org/10.3389/fimmu.2022.859387

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