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Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles

As one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic growth characteristics. The hair growth cycle is d...

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Detalles Bibliográficos
Autores principales: Lin, Xiangyu, Zhu, Liang, He, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133560/
https://www.ncbi.nlm.nih.gov/pubmed/35646909
http://dx.doi.org/10.3389/fcell.2022.899095
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author Lin, Xiangyu
Zhu, Liang
He, Jing
author_facet Lin, Xiangyu
Zhu, Liang
He, Jing
author_sort Lin, Xiangyu
collection PubMed
description As one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic growth characteristics. The hair growth cycle is divided into three continuous stages, growth (anagen), apoptosis-driven regression (catagen) and relative quiescence (telogen). And The Morphogenesis and cycle of hair follicles are regulated by a variety of signal pathways. When the signal molecules in the pathways are abnormal, it will affect the development and cycle of hair follicles, which will lead to hair follicle-related diseases.This article will review the structure, development, cycle and molecular regulation of hair follicles, in order to provide new ideas for solving diseases and forming functional hair follicle.
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spelling pubmed-91335602022-05-27 Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles Lin, Xiangyu Zhu, Liang He, Jing Front Cell Dev Biol Cell and Developmental Biology As one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic growth characteristics. The hair growth cycle is divided into three continuous stages, growth (anagen), apoptosis-driven regression (catagen) and relative quiescence (telogen). And The Morphogenesis and cycle of hair follicles are regulated by a variety of signal pathways. When the signal molecules in the pathways are abnormal, it will affect the development and cycle of hair follicles, which will lead to hair follicle-related diseases.This article will review the structure, development, cycle and molecular regulation of hair follicles, in order to provide new ideas for solving diseases and forming functional hair follicle. Frontiers Media S.A. 2022-05-12 /pmc/articles/PMC9133560/ /pubmed/35646909 http://dx.doi.org/10.3389/fcell.2022.899095 Text en Copyright © 2022 Lin, Zhu and He. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Lin, Xiangyu
Zhu, Liang
He, Jing
Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
title Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
title_full Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
title_fullStr Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
title_full_unstemmed Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
title_short Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles
title_sort morphogenesis, growth cycle and molecular regulation of hair follicles
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133560/
https://www.ncbi.nlm.nih.gov/pubmed/35646909
http://dx.doi.org/10.3389/fcell.2022.899095
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