Modulation of interleukin-6 and its effect on late vein wall injury in a stasis mouse model of deep vein thrombosis

OBJECTIVE: Deep vein thrombosis (DVT) and its sequela, post-thrombotic syndrome (PTS), remain a clinically significant problem. Interleukin-6 (IL-6) is a proinflammatory cytokine that is elevated in patients who develop PTS. We hypothesized that genetic deletion of IL-6 and the use of anti–IL-6 phar...

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Detalles Bibliográficos
Autores principales: Dowling, Abigail R., Luke, Catherine E., Cai, Qing, Pellerito, Antonio M., Obi, Andrea T., Henke, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133633/
https://www.ncbi.nlm.nih.gov/pubmed/35647566
http://dx.doi.org/10.1016/j.jvssci.2022.04.001

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