S100A8 and S100A9 are elevated in chronically threatened ischemic limb muscle and induce ischemic mitochondrial pathology in mice

OBJECTIVE: The objective of the present study was to determine whether elevated levels of S100A8 and S100A9 (S100A8/A9) alarmins contribute to ischemic limb pathology. METHODS: Gastrocnemius muscle was collected from control patients without peripheral arterial disease (PAD; n = 14) and patients wit...

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Detalles Bibliográficos
Autores principales: Salyers, Zachary R., Mariani, Vinicius, Balestrieri, Nicholas, Kumar, Ravi A., Vugman, Nicholas A., Thome, Trace, Villani, Katelyn R., Berceli, Scott A., Scali, Salvatore T., Vasilakos, Georgios, Ryan, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133641/
https://www.ncbi.nlm.nih.gov/pubmed/35647565
http://dx.doi.org/10.1016/j.jvssci.2022.03.003

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