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Prepubertal androgen signaling is required to establish male fat distribution
Fat distribution is sexually dimorphic and is associated with metabolic disease risk. It is unknown if prepubertal sex-hormone signaling influences adult fat distribution. Here, we show that karyotypically male androgen-insensitive mice exhibit pronounced subcutaneous adiposity compared with wild-ty...
Autores principales: | Sebo, Zachary L., Rodeheffer, Matthew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133643/ https://www.ncbi.nlm.nih.gov/pubmed/35487210 http://dx.doi.org/10.1016/j.stemcr.2022.04.001 |
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