Argonaute proteins regulate a specific network of genes through KLF4 in mouse embryonic stem cells

The Argonaute proteins (AGOs) are well known for their role in post-transcriptional gene silencing in the microRNA (miRNA) pathway. Here we show that in mouse embryonic stem cells, AGO1&2 serve additional functions that go beyond the miRNA pathway. Through the combined deletion of both Agos, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller, Madlen, Schaefer, Moritz, Fäh, Tara, Spies, Daniel, Hermes, Victoria, Ngondo, Richard Patryk, Peña-Hernández, Rodrigo, Santoro, Raffaella, Ciaudo, Constance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133645/
https://www.ncbi.nlm.nih.gov/pubmed/35452597
http://dx.doi.org/10.1016/j.stemcr.2022.03.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133645/
https://www.ncbi.nlm.nih.gov/pubmed/35452597
http://dx.doi.org/10.1016/j.stemcr.2022.03.014

Ejemplares similares