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Argonaute proteins regulate a specific network of genes through KLF4 in mouse embryonic stem cells

The Argonaute proteins (AGOs) are well known for their role in post-transcriptional gene silencing in the microRNA (miRNA) pathway. Here we show that in mouse embryonic stem cells, AGO1&2 serve additional functions that go beyond the miRNA pathway. Through the combined deletion of both Agos, we...

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Detalles Bibliográficos
Autores principales:	Müller, Madlen, Schaefer, Moritz, Fäh, Tara, Spies, Daniel, Hermes, Victoria, Ngondo, Richard Patryk, Peña-Hernández, Rodrigo, Santoro, Raffaella, Ciaudo, Constance
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133645/ https://www.ncbi.nlm.nih.gov/pubmed/35452597 http://dx.doi.org/10.1016/j.stemcr.2022.03.014

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