Long-term feeder-free culture of human pancreatic progenitors on fibronectin or matrix-free polymer potentiates β cell differentiation

With the aim of producing β cells for replacement therapies to treat diabetes, several protocols have been developed to differentiate human pluripotent stem cells to β cells via pancreatic progenitors. While in vivo pancreatic progenitors expand throughout development, the in vitro protocols have be...

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Detalles Bibliográficos
Autores principales: Nakamura, Akiko, Wong, Yan Fung, Venturato, Andrea, Michaut, Magali, Venkateswaran, Seshasailam, Santra, Mithun, Gonçalves, Carla, Larsen, Michael, Leuschner, Marit, Kim, Yung Hae, Brickman, Joshua, Bradley, Mark, Grapin-Botton, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133655/
https://www.ncbi.nlm.nih.gov/pubmed/35452596
http://dx.doi.org/10.1016/j.stemcr.2022.03.013

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