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Autophagy Regulation Influences β-Amyloid Toxicity in Transgenic Caenorhabditis elegans

Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by the accumulation of amyloid-beta (Aβ) proteins in the form of plaques that cause a proteostasis imbalance in the brain. Several studies have identified autophagy deficits in both AD patients and AD animal models. H...

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Detalles Bibliográficos
Autores principales: Lin, Hongru, Gao, Yehui, Zhang, Chen, Ma, Botian, Wu, Mengchen, Cui, Xianghuan, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133694/
https://www.ncbi.nlm.nih.gov/pubmed/35645788
http://dx.doi.org/10.3389/fnagi.2022.885145