Formononetin Attenuates Renal Tubular Injury and Mitochondrial Damage in Diabetic Nephropathy Partly via Regulating Sirt1/PGC-1α Pathway

Mitochondrial abnormality is one of the main factors of tubular injury in diabetic nephropathy (DN). Formononetin (FMN), a novel isoflavonoid isolated from Astragalus membranaceus, has diverse pharmacological activities. However, the beneficial effects of FMN on renal tubular impairment and mitochon...

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Detalles Bibliográficos
Autores principales: Huang, Qunwei, Chen, Hongbo, Yin, Kai, Shen, Yilan, Lin, Kanghong, Guo, Xieyi, Zhang, Xiang, Wang, Niansong, Xin, Wenfeng, Xu, Youhua, Gui, Dingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133725/
https://www.ncbi.nlm.nih.gov/pubmed/35645821
http://dx.doi.org/10.3389/fphar.2022.901234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133725/
https://www.ncbi.nlm.nih.gov/pubmed/35645821
http://dx.doi.org/10.3389/fphar.2022.901234

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