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Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy

A 29-year-old patient presented to his primary care provider complaining of a painful right inguinal swelling. He was referred for inguinal hernia repair, but during surgery, an enlarged necrotic-appearing testicle was observed and removed. Pathology demonstrated a mixed non-seminomatous germ cell t...

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Autores principales: Vehawn, Jeffrey, Choudry, Mouneeb, Mahlow, Jonathon, Agarwal, Jayant, Dechet, Christopher, Sanchez, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133747/
https://www.ncbi.nlm.nih.gov/pubmed/35646601
http://dx.doi.org/10.1016/j.eucr.2022.102120
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author Vehawn, Jeffrey
Choudry, Mouneeb
Mahlow, Jonathon
Agarwal, Jayant
Dechet, Christopher
Sanchez, Alejandro
author_facet Vehawn, Jeffrey
Choudry, Mouneeb
Mahlow, Jonathon
Agarwal, Jayant
Dechet, Christopher
Sanchez, Alejandro
author_sort Vehawn, Jeffrey
collection PubMed
description A 29-year-old patient presented to his primary care provider complaining of a painful right inguinal swelling. He was referred for inguinal hernia repair, but during surgery, an enlarged necrotic-appearing testicle was observed and removed. Pathology demonstrated a mixed non-seminomatous germ cell tumor (NSGCT) with evidence of tumor violation. After receiving BEPx3 for elevated post-operative AFP his tumor markers normalized. On surveillance, he was found to have several palpable masses around his inguinal incision. On soft tissue excision he was found to have residual teratoma within his soft tissues. We review the literature on germ cell tumor seeding and atypical recurrences.
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spelling pubmed-91337472022-05-27 Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy Vehawn, Jeffrey Choudry, Mouneeb Mahlow, Jonathon Agarwal, Jayant Dechet, Christopher Sanchez, Alejandro Urol Case Rep Oncology A 29-year-old patient presented to his primary care provider complaining of a painful right inguinal swelling. He was referred for inguinal hernia repair, but during surgery, an enlarged necrotic-appearing testicle was observed and removed. Pathology demonstrated a mixed non-seminomatous germ cell tumor (NSGCT) with evidence of tumor violation. After receiving BEPx3 for elevated post-operative AFP his tumor markers normalized. On surveillance, he was found to have several palpable masses around his inguinal incision. On soft tissue excision he was found to have residual teratoma within his soft tissues. We review the literature on germ cell tumor seeding and atypical recurrences. Elsevier 2022-05-20 /pmc/articles/PMC9133747/ /pubmed/35646601 http://dx.doi.org/10.1016/j.eucr.2022.102120 Text en © 2022 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Vehawn, Jeffrey
Choudry, Mouneeb
Mahlow, Jonathon
Agarwal, Jayant
Dechet, Christopher
Sanchez, Alejandro
Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy
title Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy
title_full Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy
title_fullStr Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy
title_full_unstemmed Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy
title_short Case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy
title_sort case of testicular nonseminomatous germ cell tumor cancer soft tissue seeding after inguinal orchiectomy
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133747/
https://www.ncbi.nlm.nih.gov/pubmed/35646601
http://dx.doi.org/10.1016/j.eucr.2022.102120
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