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Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report
INTRODUCTION AND IMPORTANCE: Pituitary apoplexy is a clinical syndrome that occurs secondary to abrupt haemorrhage or infarction and can cause a presentation with headache, visual disturbances, and various neurological deficits. Pituitary apoplexy is a rare clinical syndrome that is often misdiagnos...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133765/ https://www.ncbi.nlm.nih.gov/pubmed/35617738 http://dx.doi.org/10.1016/j.ijscr.2022.107228 |
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author | Chow, Oliver Pham, Therese He, Brandon Hort, Amy Gibson, Damien Olsson, Gemma |
author_facet | Chow, Oliver Pham, Therese He, Brandon Hort, Amy Gibson, Damien Olsson, Gemma |
author_sort | Chow, Oliver |
collection | PubMed |
description | INTRODUCTION AND IMPORTANCE: Pituitary apoplexy is a clinical syndrome that occurs secondary to abrupt haemorrhage or infarction and can cause a presentation with headache, visual disturbances, and various neurological deficits. Pituitary apoplexy is a rare clinical syndrome that is often misdiagnosed or discovered late in its clinical course due to its relatively nonspecific clinical presentation. CASE PRESENTATION: The case describes patient with a giant prolactinoma which developed haemorrhagic progression in the context of previously undiagnosed coagulopathy from idiopathic thrombocytopaenia. Transcranial (rather than transnasal) surgery was performed for evacuation and debulking. CONCLUSION: The case highlights the management of an exceedingly large adenoma in the context of coagulopathy contributing to rapid clinical progression, as well as a positive clinical outcome in a patient with restored vision and pituitary function. |
format | Online Article Text |
id | pubmed-9133765 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-91337652022-05-27 Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report Chow, Oliver Pham, Therese He, Brandon Hort, Amy Gibson, Damien Olsson, Gemma Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Pituitary apoplexy is a clinical syndrome that occurs secondary to abrupt haemorrhage or infarction and can cause a presentation with headache, visual disturbances, and various neurological deficits. Pituitary apoplexy is a rare clinical syndrome that is often misdiagnosed or discovered late in its clinical course due to its relatively nonspecific clinical presentation. CASE PRESENTATION: The case describes patient with a giant prolactinoma which developed haemorrhagic progression in the context of previously undiagnosed coagulopathy from idiopathic thrombocytopaenia. Transcranial (rather than transnasal) surgery was performed for evacuation and debulking. CONCLUSION: The case highlights the management of an exceedingly large adenoma in the context of coagulopathy contributing to rapid clinical progression, as well as a positive clinical outcome in a patient with restored vision and pituitary function. Elsevier 2022-05-20 /pmc/articles/PMC9133765/ /pubmed/35617738 http://dx.doi.org/10.1016/j.ijscr.2022.107228 Text en Crown Copyright © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Chow, Oliver Pham, Therese He, Brandon Hort, Amy Gibson, Damien Olsson, Gemma Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report |
title | Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report |
title_full | Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report |
title_fullStr | Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report |
title_full_unstemmed | Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report |
title_short | Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report |
title_sort | prolactinoma with apoplexy in the context of thrombocytopaenia: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133765/ https://www.ncbi.nlm.nih.gov/pubmed/35617738 http://dx.doi.org/10.1016/j.ijscr.2022.107228 |
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