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Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report

INTRODUCTION AND IMPORTANCE: Pituitary apoplexy is a clinical syndrome that occurs secondary to abrupt haemorrhage or infarction and can cause a presentation with headache, visual disturbances, and various neurological deficits. Pituitary apoplexy is a rare clinical syndrome that is often misdiagnos...

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Autores principales: Chow, Oliver, Pham, Therese, He, Brandon, Hort, Amy, Gibson, Damien, Olsson, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133765/
https://www.ncbi.nlm.nih.gov/pubmed/35617738
http://dx.doi.org/10.1016/j.ijscr.2022.107228
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author Chow, Oliver
Pham, Therese
He, Brandon
Hort, Amy
Gibson, Damien
Olsson, Gemma
author_facet Chow, Oliver
Pham, Therese
He, Brandon
Hort, Amy
Gibson, Damien
Olsson, Gemma
author_sort Chow, Oliver
collection PubMed
description INTRODUCTION AND IMPORTANCE: Pituitary apoplexy is a clinical syndrome that occurs secondary to abrupt haemorrhage or infarction and can cause a presentation with headache, visual disturbances, and various neurological deficits. Pituitary apoplexy is a rare clinical syndrome that is often misdiagnosed or discovered late in its clinical course due to its relatively nonspecific clinical presentation. CASE PRESENTATION: The case describes patient with a giant prolactinoma which developed haemorrhagic progression in the context of previously undiagnosed coagulopathy from idiopathic thrombocytopaenia. Transcranial (rather than transnasal) surgery was performed for evacuation and debulking. CONCLUSION: The case highlights the management of an exceedingly large adenoma in the context of coagulopathy contributing to rapid clinical progression, as well as a positive clinical outcome in a patient with restored vision and pituitary function.
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spelling pubmed-91337652022-05-27 Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report Chow, Oliver Pham, Therese He, Brandon Hort, Amy Gibson, Damien Olsson, Gemma Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Pituitary apoplexy is a clinical syndrome that occurs secondary to abrupt haemorrhage or infarction and can cause a presentation with headache, visual disturbances, and various neurological deficits. Pituitary apoplexy is a rare clinical syndrome that is often misdiagnosed or discovered late in its clinical course due to its relatively nonspecific clinical presentation. CASE PRESENTATION: The case describes patient with a giant prolactinoma which developed haemorrhagic progression in the context of previously undiagnosed coagulopathy from idiopathic thrombocytopaenia. Transcranial (rather than transnasal) surgery was performed for evacuation and debulking. CONCLUSION: The case highlights the management of an exceedingly large adenoma in the context of coagulopathy contributing to rapid clinical progression, as well as a positive clinical outcome in a patient with restored vision and pituitary function. Elsevier 2022-05-20 /pmc/articles/PMC9133765/ /pubmed/35617738 http://dx.doi.org/10.1016/j.ijscr.2022.107228 Text en Crown Copyright © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Chow, Oliver
Pham, Therese
He, Brandon
Hort, Amy
Gibson, Damien
Olsson, Gemma
Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report
title Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report
title_full Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report
title_fullStr Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report
title_full_unstemmed Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report
title_short Prolactinoma with apoplexy in the context of thrombocytopaenia: A case report
title_sort prolactinoma with apoplexy in the context of thrombocytopaenia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133765/
https://www.ncbi.nlm.nih.gov/pubmed/35617738
http://dx.doi.org/10.1016/j.ijscr.2022.107228
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