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EZH2-Mediated H3K27me3 Targets Transcriptional Circuits of Neuronal Differentiation

The Polycomb Repressive Complex 2 (PRC2) plays important roles in the epigenetic regulation of cellular development and differentiation through H3K27me3-dependent transcriptional repression. Aberrant PRC2 activity has been associated with cancer and neurodevelopmental disorders, particularly with re...

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Detalles Bibliográficos
Autores principales:	Buontempo, Serena, Laise, Pasquale, Hughes, James M., Trattaro, Sebastiano, Das, Vivek, Rencurel, Chantal, Testa, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9133892/ https://www.ncbi.nlm.nih.gov/pubmed/35645710 http://dx.doi.org/10.3389/fnins.2022.814144

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