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Applying molecular networking for targeted isolation of depsipeptides

LC-HRMS/MS molecular networking enabled the targeted isolation of three new neoantimycin analogs (1, 3, 5) and two known ones (2, 4) from the culture broth of Streptomyces conglobatus RJ8. After derivatization into C1-hydroxyl form compounds (6–10) respectively, the absolute structures of 1–5 were c...

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Detalles Bibliográficos
Autores principales: Lin, Xiao, Chai, Ling, Zhu, Hong Rui, Zhou, Yongjun, Shen, Yaoyao, Chen, Kai Hao, Sun, Fan, Liu, Bu Ming, Xu, Shi Hai, Lin, Hou Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134009/
https://www.ncbi.nlm.nih.gov/pubmed/35747077
http://dx.doi.org/10.1039/d0ra09388b