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Bumetanide Effects on Resting-State EEG in Tuberous Sclerosis Complex in Relation to Clinical Outcome: An Open-Label Study

Neuronal excitation-inhibition (E/I) imbalances are considered an important pathophysiological mechanism in neurodevelopmental disorders. Preclinical studies on tuberous sclerosis complex (TSC), suggest that altered chloride homeostasis may impair GABAergic inhibition and thereby E/I-balance regulat...

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Detalles Bibliográficos
Autores principales: Juarez-Martinez, Erika L., van Andel, Dorinde M., Sprengers, Jan J., Avramiea, Arthur-Ervin, Oranje, Bob, Scheepers, Floortje E., Jansen, Floor E., Mansvelder, Huibert D., Linkenkaer-Hansen, Klaus, Bruining, Hilgo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134117/
https://www.ncbi.nlm.nih.gov/pubmed/35645706
http://dx.doi.org/10.3389/fnins.2022.879451