Characterization of erenumab and rimegepant on calcitonin gene-related peptide induced responses in Xenopus Laevis oocytes expressing the calcitonin gene-related peptide receptor and the amylin-1 receptor

BACKGROUND: The clinical use of calcitonin gene-related peptide receptor (CGRP-R) antagonists and monoclonal antibodies against CGRP and CGRP-R has offered new treatment possibilities for migraine patients. CGRP activates both the CGRP-R and structurally related amylin 1 receptor (AMY(1)-R). The rel...

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Detalles Bibliográficos
Autores principales: Hage La Cour, Sanne, Juhler, Kiki, Kogelman, Lisette J. A., Olesen, Jes, Klærke, Dan Arne, Kristensen, David Møbjerg, Jansen-Olesen, Inger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134599/
https://www.ncbi.nlm.nih.gov/pubmed/35614383
http://dx.doi.org/10.1186/s10194-022-01425-9

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