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PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway

BACKGROUND: Phosphoglucomutase 1 (PGM1) is known for its involvement in cancer pathogenesis. However, its biological role in colorectal cancer (CRC) has remained unknown. Here, we studied the functions and mechanisms of PGM1 in CRC. METHODS: We verified PGM-1 as a differentially expressed gene (DEG)...

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Detalles Bibliográficos
Autores principales: Zheng, Zhewen, Zhang, Xue, Bai, Jian, Long, Long, Liu, Di, Zhou, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134613/
https://www.ncbi.nlm.nih.gov/pubmed/35614441
http://dx.doi.org/10.1186/s12935-022-02545-7