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Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists

BACKGROUND: Machine learning, especially deep learning, is becoming more and more relevant in research and development in the medical domain. For all the supervised deep learning applications, data is the most critical factor in securing successful implementation and sustaining the progress of the m...

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Autores principales: Krenzer, Adrian, Makowski, Kevin, Hekalo, Amar, Fitting, Daniel, Troya, Joel, Zoller, Wolfram G., Hann, Alexander, Puppe, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134702/
https://www.ncbi.nlm.nih.gov/pubmed/35614504
http://dx.doi.org/10.1186/s12938-022-01001-x
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author Krenzer, Adrian
Makowski, Kevin
Hekalo, Amar
Fitting, Daniel
Troya, Joel
Zoller, Wolfram G.
Hann, Alexander
Puppe, Frank
author_facet Krenzer, Adrian
Makowski, Kevin
Hekalo, Amar
Fitting, Daniel
Troya, Joel
Zoller, Wolfram G.
Hann, Alexander
Puppe, Frank
author_sort Krenzer, Adrian
collection PubMed
description BACKGROUND: Machine learning, especially deep learning, is becoming more and more relevant in research and development in the medical domain. For all the supervised deep learning applications, data is the most critical factor in securing successful implementation and sustaining the progress of the machine learning model. Especially gastroenterological data, which often involves endoscopic videos, are cumbersome to annotate. Domain experts are needed to interpret and annotate the videos. To support those domain experts, we generated a framework. With this framework, instead of annotating every frame in the video sequence, experts are just performing key annotations at the beginning and the end of sequences with pathologies, e.g., visible polyps. Subsequently, non-expert annotators supported by machine learning add the missing annotations for the frames in-between. METHODS: In our framework, an expert reviews the video and annotates a few video frames to verify the object’s annotations for the non-expert. In a second step, a non-expert has visual confirmation of the given object and can annotate all following and preceding frames with AI assistance. After the expert has finished, relevant frames will be selected and passed on to an AI model. This information allows the AI model to detect and mark the desired object on all following and preceding frames with an annotation. Therefore, the non-expert can adjust and modify the AI predictions and export the results, which can then be used to train the AI model. RESULTS: Using this framework, we were able to reduce workload of domain experts on average by a factor of 20 on our data. This is primarily due to the structure of the framework, which is designed to minimize the workload of the domain expert. Pairing this framework with a state-of-the-art semi-automated AI model enhances the annotation speed further. Through a prospective study with 10 participants, we show that semi-automated annotation using our tool doubles the annotation speed of non-expert annotators compared to a well-known state-of-the-art annotation tool. CONCLUSION: In summary, we introduce a framework for fast expert annotation for gastroenterologists, which reduces the workload of the domain expert considerably while maintaining a very high annotation quality. The framework incorporates a semi-automated annotation system utilizing trained object detection models. The software and framework are open-source.
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spelling pubmed-91347022022-05-27 Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists Krenzer, Adrian Makowski, Kevin Hekalo, Amar Fitting, Daniel Troya, Joel Zoller, Wolfram G. Hann, Alexander Puppe, Frank Biomed Eng Online Research BACKGROUND: Machine learning, especially deep learning, is becoming more and more relevant in research and development in the medical domain. For all the supervised deep learning applications, data is the most critical factor in securing successful implementation and sustaining the progress of the machine learning model. Especially gastroenterological data, which often involves endoscopic videos, are cumbersome to annotate. Domain experts are needed to interpret and annotate the videos. To support those domain experts, we generated a framework. With this framework, instead of annotating every frame in the video sequence, experts are just performing key annotations at the beginning and the end of sequences with pathologies, e.g., visible polyps. Subsequently, non-expert annotators supported by machine learning add the missing annotations for the frames in-between. METHODS: In our framework, an expert reviews the video and annotates a few video frames to verify the object’s annotations for the non-expert. In a second step, a non-expert has visual confirmation of the given object and can annotate all following and preceding frames with AI assistance. After the expert has finished, relevant frames will be selected and passed on to an AI model. This information allows the AI model to detect and mark the desired object on all following and preceding frames with an annotation. Therefore, the non-expert can adjust and modify the AI predictions and export the results, which can then be used to train the AI model. RESULTS: Using this framework, we were able to reduce workload of domain experts on average by a factor of 20 on our data. This is primarily due to the structure of the framework, which is designed to minimize the workload of the domain expert. Pairing this framework with a state-of-the-art semi-automated AI model enhances the annotation speed further. Through a prospective study with 10 participants, we show that semi-automated annotation using our tool doubles the annotation speed of non-expert annotators compared to a well-known state-of-the-art annotation tool. CONCLUSION: In summary, we introduce a framework for fast expert annotation for gastroenterologists, which reduces the workload of the domain expert considerably while maintaining a very high annotation quality. The framework incorporates a semi-automated annotation system utilizing trained object detection models. The software and framework are open-source. BioMed Central 2022-05-25 /pmc/articles/PMC9134702/ /pubmed/35614504 http://dx.doi.org/10.1186/s12938-022-01001-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Krenzer, Adrian
Makowski, Kevin
Hekalo, Amar
Fitting, Daniel
Troya, Joel
Zoller, Wolfram G.
Hann, Alexander
Puppe, Frank
Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists
title Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists
title_full Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists
title_fullStr Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists
title_full_unstemmed Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists
title_short Fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists
title_sort fast machine learning annotation in the medical domain: a semi-automated video annotation tool for gastroenterologists
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134702/
https://www.ncbi.nlm.nih.gov/pubmed/35614504
http://dx.doi.org/10.1186/s12938-022-01001-x
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