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Assessment of a polygenic hazard score for the onset of pre-clinical Alzheimer’s disease

ABSTRACT: BACKGROUND: With a growing number of loci associated with late-onset (sporadic) Alzheimer’s disease (AD), the polygenic contribution to AD is now well established. The development of polygenic risk score approaches have shown promising results for identifying individuals at higher risk of...

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Detalles Bibliográficos
Autores principales: Vacher, Michael, Doré, Vincent, Porter, Tenielle, Milicic, Lidija, Villemagne, Victor L., Bourgeat, Pierrick, Burnham, Sam C., Cox, Timothy, Masters, Colin L., Rowe, Christopher C., Fripp, Jurgen, Doecke, James D., Laws, Simon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134703/
https://www.ncbi.nlm.nih.gov/pubmed/35619096
http://dx.doi.org/10.1186/s12864-022-08617-2