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Assessment of a polygenic hazard score for the onset of pre-clinical Alzheimer’s disease
ABSTRACT: BACKGROUND: With a growing number of loci associated with late-onset (sporadic) Alzheimer’s disease (AD), the polygenic contribution to AD is now well established. The development of polygenic risk score approaches have shown promising results for identifying individuals at higher risk of...
Autores principales: | Vacher, Michael, Doré, Vincent, Porter, Tenielle, Milicic, Lidija, Villemagne, Victor L., Bourgeat, Pierrick, Burnham, Sam C., Cox, Timothy, Masters, Colin L., Rowe, Christopher C., Fripp, Jurgen, Doecke, James D., Laws, Simon M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134703/ https://www.ncbi.nlm.nih.gov/pubmed/35619096 http://dx.doi.org/10.1186/s12864-022-08617-2 |
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