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A proteomics-MM/PBSA dual approach for the analysis of SARS-CoV-2 main protease substrate peptide specificity

The main protease M(pro) of SARS-CoV-2 is a well-studied major drug target. Additionally, it has been linked to this virus’ pathogenicity, possibly through off-target effects. It is also an interesting diagnostic target. To obtain more data on possible substrates as well as to assess the enzyme’s pr...

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Detalles Bibliográficos
Autores principales:	Gallo, Gloria, Barcick, Uilla, Coelho, Camila, Salardani, Murilo, Camacho, Maurício F., Cajado-Carvalho, Daniela, Loures, Flávio V., Serrano, Solange M.T., Hardy, Leon, Zelanis, André, Würtele, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134770/ https://www.ncbi.nlm.nih.gov/pubmed/35644302 http://dx.doi.org/10.1016/j.peptides.2022.170814

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