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SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?

This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for o...

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Autores principales: Pereira, Maria Fernanda Bádue, Suguita, Priscila, Litvinov, Nadia, Farhat, Sylvia Costa Lima, de Paula, Camila Sanson Yoshino, Lázari, Carolina dos Santos, Bedê, Pedro Vale, Framil, Juliana Valeria de Souza, Bueno, Catarina, Branas, Priscila Cristina Abduch Adas, Guimarães, Irina Monteiro da Costa, Leite, Marcia Marques, Navega, Ana Carolina Barsaglini, Nanbu, Danilo Yamamoto, Schvartsman, Claudio, Pinho, João Renato Rebello, Silva, Clovis Artur Almeida, Marques, Heloisa Helena de Sousa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto de Medicina Tropical de São Paulo 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134860/
https://www.ncbi.nlm.nih.gov/pubmed/35648987
http://dx.doi.org/10.1590/S1678-9946202264034
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author Pereira, Maria Fernanda Bádue
Suguita, Priscila
Litvinov, Nadia
Farhat, Sylvia Costa Lima
de Paula, Camila Sanson Yoshino
Lázari, Carolina dos Santos
Bedê, Pedro Vale
Framil, Juliana Valeria de Souza
Bueno, Catarina
Branas, Priscila Cristina Abduch Adas
Guimarães, Irina Monteiro da Costa
Leite, Marcia Marques
Navega, Ana Carolina Barsaglini
Nanbu, Danilo Yamamoto
Schvartsman, Claudio
Pinho, João Renato Rebello
Silva, Clovis Artur Almeida
Marques, Heloisa Helena de Sousa
author_facet Pereira, Maria Fernanda Bádue
Suguita, Priscila
Litvinov, Nadia
Farhat, Sylvia Costa Lima
de Paula, Camila Sanson Yoshino
Lázari, Carolina dos Santos
Bedê, Pedro Vale
Framil, Juliana Valeria de Souza
Bueno, Catarina
Branas, Priscila Cristina Abduch Adas
Guimarães, Irina Monteiro da Costa
Leite, Marcia Marques
Navega, Ana Carolina Barsaglini
Nanbu, Danilo Yamamoto
Schvartsman, Claudio
Pinho, João Renato Rebello
Silva, Clovis Artur Almeida
Marques, Heloisa Helena de Sousa
author_sort Pereira, Maria Fernanda Bádue
collection PubMed
description This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for other respiratory pathogens (ORP). Patients with laboratory-confirmed COVID-19 or ORP were included. We evaluated 76 pediatric COVID-19 infections and 157 other respiratory virus infections. Rhinovirus occurred in 132/157 (84%). COVID-19 patients who were significantly older, had more fevers, headaches and pneumonia than those with ORP. The median white blood cell count was lower in patients with SARS-CoV-2 than in those with ORP (6,470 versus 8,170; p=0.02). COVID-19 patients had significantly worse symptoms than those with ORP.
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spelling pubmed-91348602022-06-07 SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population? Pereira, Maria Fernanda Bádue Suguita, Priscila Litvinov, Nadia Farhat, Sylvia Costa Lima de Paula, Camila Sanson Yoshino Lázari, Carolina dos Santos Bedê, Pedro Vale Framil, Juliana Valeria de Souza Bueno, Catarina Branas, Priscila Cristina Abduch Adas Guimarães, Irina Monteiro da Costa Leite, Marcia Marques Navega, Ana Carolina Barsaglini Nanbu, Danilo Yamamoto Schvartsman, Claudio Pinho, João Renato Rebello Silva, Clovis Artur Almeida Marques, Heloisa Helena de Sousa Rev Inst Med Trop Sao Paulo Brief Communication This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for other respiratory pathogens (ORP). Patients with laboratory-confirmed COVID-19 or ORP were included. We evaluated 76 pediatric COVID-19 infections and 157 other respiratory virus infections. Rhinovirus occurred in 132/157 (84%). COVID-19 patients who were significantly older, had more fevers, headaches and pneumonia than those with ORP. The median white blood cell count was lower in patients with SARS-CoV-2 than in those with ORP (6,470 versus 8,170; p=0.02). COVID-19 patients had significantly worse symptoms than those with ORP. Instituto de Medicina Tropical de São Paulo 2022-05-25 /pmc/articles/PMC9134860/ /pubmed/35648987 http://dx.doi.org/10.1590/S1678-9946202264034 Text en https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Pereira, Maria Fernanda Bádue
Suguita, Priscila
Litvinov, Nadia
Farhat, Sylvia Costa Lima
de Paula, Camila Sanson Yoshino
Lázari, Carolina dos Santos
Bedê, Pedro Vale
Framil, Juliana Valeria de Souza
Bueno, Catarina
Branas, Priscila Cristina Abduch Adas
Guimarães, Irina Monteiro da Costa
Leite, Marcia Marques
Navega, Ana Carolina Barsaglini
Nanbu, Danilo Yamamoto
Schvartsman, Claudio
Pinho, João Renato Rebello
Silva, Clovis Artur Almeida
Marques, Heloisa Helena de Sousa
SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
title SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
title_full SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
title_fullStr SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
title_full_unstemmed SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
title_short SARS-CoV-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
title_sort sars-cov-2 and rhinovirus infections: are there differences in clinical presentation, laboratory abnormalities, and outcomes in the pediatric population?
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134860/
https://www.ncbi.nlm.nih.gov/pubmed/35648987
http://dx.doi.org/10.1590/S1678-9946202264034
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