USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ

Mutations and altered expression of deubiquitinating enzymes (DUBs) profoundly influence tumor progression. Ubiquitin-specific protease 1 (USP1) is a well-characterized human DUB reportedly overexpressed in and associated with maintaining the mesenchymal stem cell status of osteosarcoma (OS); howeve...

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Detalles Bibliográficos
Autores principales: Yuan, Putao, Feng, Zhenhua, Huang, Hai, Wang, Gangliang, Chen, Zhijun, Xu, Guang, Xie, Ziang, Jie, Zhiwei, Zhao, Xiangde, Ma, Qingliang, Wang, Shiyu, Shen, Yang, Huang, Yizhen, Han, Ying, Ye, Huali, Wang, Jiying, Shi, Peihua, Sun, Xuewu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9134912/
https://www.ncbi.nlm.nih.gov/pubmed/35637948
http://dx.doi.org/10.7150/ijbs.65428

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