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The involvement of CYP1A2 in biodegradation of dioxins in pigs

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is one of the most harmful chemicals showing resistance to biodegradation. The majority of TCDD effects is mediated by the aryl hydrocarbon receptor (AhR) pathway. TCDD binding to AhR results in the activation of cytochrome P450 enzymes (CYP1A1, CYP1A2, CYP...

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Detalles Bibliográficos
Autores principales: Swigonska, Sylwia, Molcan, Tomasz, Nynca, Anna, Ciereszko, Renata E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135293/
https://www.ncbi.nlm.nih.gov/pubmed/35617319
http://dx.doi.org/10.1371/journal.pone.0267162

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