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Regulating Acidosis and Relieving Hypoxia by Platelet Membrane-Coated Nanoparticle for Enhancing Tumor Chemotherapy

Acidosis and hypoxia of tumor remain a great challenge for cancer therapy. Herein, we developed Hb-LOX-DOX-ZIF8@platelet membrane nanoparticles (H-L-D-Z@PM NPs) to address this problem. Lactate oxidase (LOX) could deplete intratumoral lactate adequately and amplify oxidative stress efficiently. In t...

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Detalles Bibliográficos
Autores principales:	Luo, Xingyu, Cao, Jian, Yu, Jianming, Dai, Dongqing, Jiang, Wei, Feng, Yahui, Hu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135319/ https://www.ncbi.nlm.nih.gov/pubmed/35646869 http://dx.doi.org/10.3389/fbioe.2022.885105

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