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Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis
Atopic dermatitis (AD) is one of the most common skin disorders among children. Disease etiology involves genetic and environmental factors, with 29 independent AD risk loci enriched for risk allele-dependent gene expression in the skin and CD4(+) T cell compartments. We investigated the potential e...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135339/ https://www.ncbi.nlm.nih.gov/pubmed/35576187 http://dx.doi.org/10.1371/journal.pgen.1009973 |