Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis

Atopic dermatitis (AD) is one of the most common skin disorders among children. Disease etiology involves genetic and environmental factors, with 29 independent AD risk loci enriched for risk allele-dependent gene expression in the skin and CD4(+) T cell compartments. We investigated the potential e...

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Detalles Bibliográficos
Autores principales: Eapen, Amy A., Parameswaran, Sreeja, Forney, Carmy, Edsall, Lee E., Miller, Daniel, Donmez, Omer, Dunn, Katelyn, Lu, Xiaoming, Granitto, Marissa, Rowden, Hope, Magier, Adam Z., Pujato, Mario, Chen, Xiaoting, Kaufman, Kenneth, Bernstein, David I., Devonshire, Ashley L., Rothenberg, Marc E., Weirauch, Matthew T., Kottyan, Leah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135339/
https://www.ncbi.nlm.nih.gov/pubmed/35576187
http://dx.doi.org/10.1371/journal.pgen.1009973

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