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Deactivation of the antiviral state by rabies virus through targeting and accumulation of persistently phosphorylated STAT1

Antagonism of the interferon (IFN)-mediated antiviral state is critical to infection by rabies virus (RABV) and other viruses, and involves interference in the IFN induction and signaling pathways in infected cells, as well as deactivation of the antiviral state in cells previously activated by IFN....

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Detalles Bibliográficos
Autores principales: Manokaran, Gayathri, Audsley, Michelle D., Funakoda, Haruka, David, Cassandra T., Garnham, Katherine A., Rawlinson, Stephen M., Deffrasnes, Celine, Ito, Naoto, Moseley, Gregory W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135343/
https://www.ncbi.nlm.nih.gov/pubmed/35576230
http://dx.doi.org/10.1371/journal.ppat.1010533