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Gut Metabolite Urolithin A Inhibits Osteoclastogenesis and Senile Osteoporosis by Enhancing the Autophagy Capacity of Bone Marrow Macrophages

Senile osteoporosis (SOP) is a systemic bone disease that is significantly associated with age and eventually leads to deteriorated bone strength and increased fracture risk. Urolithin A (Uro-A) is a gut microbiome-derived compound that is mainly produced from pomegranates and some nuts. Uro-A has a...

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Detalles Bibliográficos
Autores principales:	Tao, Huaqiang, Tao, Yunxia, Yang, Chen, Li, Wenming, Zhang, Wei, Li, Xueyan, Gu, Ye, Hong, Yujing, Yang, Huilin, Liu, Yu, Yang, Xing, Geng, Dechun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9135380/ https://www.ncbi.nlm.nih.gov/pubmed/35645801 http://dx.doi.org/10.3389/fphar.2022.875611

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